• Edgar,R.J., van Hensbergen, V.P., Ruda, A., Turner, A.G., Deng, P., Le Breton, Y., El-Sayed, N.M., Belew, A.T., McIver, K.S., McEwan, A.G., Morris, A.J., Lambeau, G., Walker, M.J., Rush, J.S., Korotkov, K.V., Widmalm, G., van Sorge, N.M., Korotkova (2019). Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides. Nat. Chem. Biol., In production.

  • Christensen, S.M., Belew, A.T., El-Sayed, N.M., Tafuri, W.L., Silveira, F.T., Mosser, D.M. (2019). Host and parasite responses in human diffuse cutaneous leishmaniasis caused by L. amazonensis. PLoS Neg.Trop. Dis., In production.

  • Banks, D.A., Ahlbrand, S.E., Hughitt, V.K., Shah, S., Vogel, S.N., El-Sayed, N.M., Briken, V. (2019). Mycobacterium tuberculosis inhibits autocrine type I interferon signaling to increase intracellular survival. J. Immunol, 2019, doi:10.4049/jimmunol.1801303 BioRxiv J Immunol

  • Valdes, K., Sundar, G.S., Belew, A.T., Islam, E., El-Sayed, N.M., Le Breton, Y., McIver, K.S. (2018). Glucose Levels Alter the Mga Virulence Regulon in the Group A Streptococcus. Sci. Rep., 2018 Mar 21;8(1):4971. doi: 10.1038/s41598-018-23366-7. PubMed Sci Rep

  • Hossain. M., Alam, M., Khaleque, A., Islam, S., Sadique, A., Khan, N., Halim, Z., Sarker, M., El-Sayed, N.M., Huq, A., Ahsan, G.U., Colwell, R.R. (2018). Virulence-Related Genes Identified from the Genome Sequence of the Non-O1/Non-O139 Vibrio cholerae Strain VcN1, Isolated from Dhaka, Bangladesh. Genome Announc., 2018 Mar 8;6(10). pii: e01513-17. doi: 10.1128/genomeA.01513-17. PubMed Genome A

  • Geis-Asteggiante, L., Belew, A.T., Clements, V.K., Edwards, N.J., Ostrand-Rosenberg, S., El-Sayed, N.M., Fenselau, C. (2018). Differential content of proteins, mRNAs, and miRNAs suggests that MDSC and their exosomes may mediate distinct immune suppressive functions. J. Proteome Res., 2018 Jan 5;17(1):486-498. doi: 10.1021/acs.jproteome.7b00646. Epub 2017 Nov 27. PubMed J Prot Res

  • Belew, A.T., Junqueira, C., Rodrigues-Luiz, G.F., Valente, B.M., Oliveira, A.O., Polidoro, R.B., Zuccherato, L.W., Bartholomeu, D.C., Schenkman, S., Gazzinelli, R.T., Burleigh, B.A., El-Sayed, N.M., Teixeira, S.T. (2017). Comparative transcriptome profiling of virulent and non-virulent Trypanosoma cruzi underlines the role of surface proteins during infection. PLoS Pathogens, 2017 Dec 14;13(12):e1006767. doi: 10.1371/journal.ppat.1006767. eCollection 2017 Dec. PubMed PMC PLoS Path

  • Smircich, P., El-Sayed, N.M., Garat, B. (2017). Intrinsic DNA curvature contributes indirect DNA readout effects in trypanosomes. BMC Res. Notes, 2017 Nov 9;10(1):585. doi: 10.1186/s13104-017-2908-y. PubMed PMC BMC Res Notes

  • Le Breton, Y., Belew, A.T., Freiberg, J.A., Sundar, G.S., Islam, E., Lieberman, J., Shirtliff, M.E., Tettelin, H., El-Sayed, N.M., McIver, K.S. (2017). Genome-wide discovery of novel M1T1 group A streptococcal determinants important for fitness and virulence during soft-tissue infection. PLoS Pathogens, 13(8), e1006584. doi: 10.1371/journal.ppat.1006584. PubMed PMC PLoS Path

  • Inbar, E., Hughitt, V.K., Dillon, L.A.L., Ghosh, K., El-Sayed, N.M., Sacks, D.L. (2017). The Transcriptome of Leishmania major Developmental Stages in Their Natural Sand Fly Vector. mBio, 8(2), e00029-17. doi: 10.1128/mBio.00029-17. PubMed PMC mBio

  • Quigley, J., Hughitt, V.K., Velikovsky, C.A., Mariuzza, R., El-Sayed, N.M., Briken, V. (2017). The cell wall lipid PDIM mediates phagosomal escape and host cell exit of Mycobacterium tuberculosis. mBio, 8(2), e00148-17. DOI: 10.1128/mBio.00148-17. PubMed PMC mBio

  • Stevens, A.M., Smith, A.C., Marbach-Ad, G., Balcom, S.A., Buchner, J., Daniel, S.L., DeStefano, J.J., El-Sayed, N.M., Frauwirth, K., Lee, V.T., McIver, K.S., Melville, S.B., Mosser, D.M., Popham, D.L., Scharf, B.E., Schubot, F.D., Seyler, R.W., Shields, P.A., Song, W., Stein, D.C., Stewart, R.C., Thompson, K.V., Yang, Z., Yarwood, S.A. (2017) Using a Concept Inventory to Reveal Student Thinking Associated with Common Misconceptions about Antibiotic Resistance. J. Microbiol. Biol. Educ., 18(1). pii: 18.1.10. doi: 10.1128/jmbe.v18i1.1281. PubMed PMC

  • Bartholomeu, D.C., Teixeira, S.M.R & El-Sayed, N.M. (2017). Genetics of Trypanosoma cruzi: Nuclear Genome. In J. Telleria & M. Tibayrenc (Eds.), American Trypanosomiasis Chagas Disease: One Hundred Years of Research (pp. 429-446). Amsterdam: Elsevier.

  • Vega, L.A, Valdes, K.M., Sundar, G.S, Belew, A.T., Islam, E., Berge, J., Curry, P., Chen, S., El-Sayed, N.M., Breton, Y.L., McIver, K.S. (2017). The transcriptional regulator CpsY is important for innate immune evasion in Streptococcus pyogenes. Infection and Immunity. DOI: 10.1128/IAI.00925-16 PubMed PMC IAI

  • Christensen, S.M., Dillon, L.A., Carvalho, L.P, Passos, S., Novais, F.O., Hughitt, V.K., Beiting D.P., Carvalho, E.M., Scott, P., El-Sayed, N.M., Mosser, D.M. (2016). Meta-transcriptome profiling of the human-Leishmania braziliensis cutaneous lesion. PLoS Neglected Tropical Diseases, 10(9), e0004992. DOI: 10.1371/journal.pntd.0004992 PubMed PMC PLoS Negl Trop Dis

  • Houston-Ludlam, G.A., Belew, A.T., & El-Sayed, N.M. (2016). Comparative transcriptome profiling of human foreskin fibroblasts infected with the Sylvio and Y strains of Trypanosoma cruzi. PLoS One, 11(8), e0159197. DOI: 10.1371/journal.pone.0159197 PubMed PLoS One

  • Fernandes, M.C.*, Dillon, L.A.L.*, Belew, A.T., Corrada Bravo, H., Mosser, D.M., & El-Sayed, N.M. (2016). Dual transcriptome profiling of Leishmania-infected human macrophages reveals distinct reprogramming signatures. mBio, 7(3), e00027-16. DOI: 10.1128/mBio.00027-16 PubMed mBio

  • Li, Y., Shah-Simpson, S., Okrah, K., Belew, A.T., Choi, J., Caradonna, K.L., Padmanabhan, P., Ndegwa, D. M., Temanni, M.R., Corrada Bravo, H., El-Sayed, N.M.*, & Burleigh, B.A.* (2016). Transcriptome remodeling in Trypanosoma cruzi and human cells during intracellular infection. PLoS Pathogens, 12(4), e1005511. DOI: 10.1371/journal.ppat.1005511 PubMed PLoS Pathog

  • Valdes, K.M., Sundar, G.S., Vega, L.A., Belew. A.T., Islam, E., Binet, R., El-Sayed, N.M., Le Breton, Y., & McIver. K.S. (2016). The fruRBA operon is necessary for Group A Streptococcal growth in fructose and for resistance to neutrophil killing during growth in whole human blood. Infection and Immunity, 84(4), 1016-31. DOI: 10.1128/IAI.01296-15 PubMed Infect Immun

  • Dillon, L.A.L., Okrah, K., Suresh, R., Corrada Bravo, H., Mosser, D.M., & El-Sayed, N.M. (2015). Simultaneous transcriptional profiling of Leishmania major parasites and murine macrophages. BMC Genomics, 16(1), 1108. DOI: 10.1186/s12864-015-2237-2 PubMed BMC Gen

  • Dillon, L.A., Okrah, K., Hughitt, V.K., Suresh, R., Li, Y., Fernandes, M.C., Belew, A.T., Corrada Bravo, H., Mosser, D.M., & El-Sayed, N.M. (2015). Transcriptomic profiling of gene expression and RNA processing during Leishmania major differentiation. Nucleic Acids Research, 43(14), 6799-813. DOI: 10.1093/nar/gkv656 PubMed NAR

  • Fleming, B.D., Chandrasekaran, P., Dillon, L.A., Dalby, E., Suresh, R., Sarkar, A., El-Sayed, N.M., & Mosser, D.M. (2015). The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling. Journal of Leukocyte Biology, 98(3), 395-407. DOI: 10.1189/jlb.2A1114-560R PubMed J Leuk Bio

  • Le Breton, Y., Belew, A.T., Valdes, K.M., Islam, E., Curry, P., Tettelin, H., Shirtliff, M.E., El-Sayed, N.M., & McIver, K.S. (2015). Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes. Nature Scientific Reports, 5, 9838. DOI: 10.1038/srep09838 PubMed Nat Sci Rep

  • Smircich, P., Forteza, D., El-Sayed, N.M., & Garat, B. (2013). Genomic analysis of sequence-dependent DNA curvature in Leishmania. PLoS One, 8(4), e63068. DOI: 10.1371/journal.pone.0063068 PubMed PLoS One

  • Savage, A.F., Cerqueira, G.C., Regmi, S., Wu, Y., El-Sayed, N.M., & Aksoy, S. (2012). Transcript expression analysis of putative Trypanosoma brucei GPI-anchored surface proteins during development in the tsetse and mammalian hosts. PLoS Neg. Trop. Dis., 6(6), e1708. DOI: 10.1371/journal.pntd.0001708 PubMed PLoS Negl Trop Dis

  • Waisberg, M., Cerqueira, G.C., Yager, S.B., Francischetti, I.M., Lu, J., Gera, N., Srinivasan, P., Miura, K., Rada, B., Lukszo, J., Barbian, K.D., Leto, T.L., Porcella, S.F., Narum, D.L., El-Sayed, N., Miller, L.H., & Pierce, S.K. (2012). Plasmodium falciparum merozoite surface protein 1 blocks the proinflammatory protein S100P. Proceedings of the National Academy of Sciences USA, 109(14), 5429-34. DOI: 10.1073/pnas.1202689109 PubMed PNAS

  • Choi, J., & El-Sayed, N.M. (2011). Functional Genomics of Trypanosomatids. Parasite Immunology, 34(2-3), 72-9. DOI: 10.1111/j.1365-3024.2011.01347.x PubMed Parasite Immunol

  • Teixeira, S.M., El-Sayed, N.M., & Araújo, P.R. (2011). The genome and its implications. Advances in Parasitology, 75, 209-30. DOI: 10.1016/B978-0-12-385863-4.00010-1 PubMed

  • Simões, M.C., Lee, J., Djikeng, A., Cerqueira, G.C., Zerlotini, A., da Silva-Pereira, R.A., Dalby, A.R., LoVerde, P., El-Sayed, N.M., & Oliveira, G. (2011). Identification of Schistosoma mansoni microRNAs. BMC Genomics, 12, 47. DOI: 10.1186/1471-2164-12-47 PubMed BMC Gen

  • Marbach-Ad, G., McAdams, K., Benson, S., Briken, V., Cathcart, L., Chase, M., El-Sayed, N., Frauwirth, K., Fredericksen, B., Joseph, S., Lee, V., McIver, K., Mosser, D., Quimby, B., Shields, P., Song, W., Stein, D., Stewart, R., Thompson, K., & Smith, A. (2010). A model for using a concept inventory as a tool for students' assessment and faculty professional development. CBE Life Sciences Education, 9(4), 408-416. DOI: 10.1187/cbe.10-05-0069 PubMed CBE Life Sci Ed

  • Severance, S., Rajagopal, A., Rao, A.U., Cerqueira, G.C., Mitreva, M., El-Sayed, N.M., Krause, M., & Hamza, I. (2010). Genome-wide analysis reveals novel genes essential for heme homeostasis in Caen­rhabditis elegans. PLoS Genetics, 6(7), e1001044. DOI: 10.1371/journal.pgen.1001044 PubMed PLoS Genetics

  • Joseph, S.J., Fernández-Robledo, J.A., Gardner, M.J., El-Sayed, N.M., Kuo, C.H., Schott, E.J., Wang, H., Kissinger, J.C., & Vasta, G.R. (2010). The Alveolate Perkinsus marinus: biological insights from EST gene discovery. BMC Genomics, 11, 228. DOI: 10.1186/1471-2164-11-228 PubMed BMC Genomics

  • Ittiprasert, W., Miller, A., Myers, J., Nene, V., El-Sayed, N.M., & Knight, M. (2009). Identification of immediate response genes dominantly expressed in juvenile resistant and susceptible Biomphalaria glabrata snails upon exposure to Schistosoma mansoni. Molecular Biochemical Parasitology, 169(1), 27-39. DOI: 10.1016/j.molbiopara.2009.09.009 PubMed

  • Nature Cover

    Berriman, M., Haas, B.J., LoVerde, P.T., Wilson, R.A., Dillon, G.P., Cerqueira, G.C., Mashiyama, S.T., Al-Lazikani, B., Andrade, L.F., Ashton, P.D., Aslett, M.A., Bartholomeu, D.C., Blandin, G., Caffrey, C.R., Coghlan, A., Coulson, R., Day, T.A., Delcher, A., DeMarco, R., Djikeng, A., Eyre, T., Gamble, J.A., Ghedin, E., Gu, Y., Hertz-Fowler, C., Hirai, H., Hirai, Y., Houston, R., Ivens, A., Johnston, D.A., Lacerda, D., Macedo, C.D., McVeigh, P., Ning, Z., Oliveira, G., Overington, J.P., Parkhill, J., Pertea, M., Pierce, R.J., Protasio, A.V., Quail, M.A., Rajandream, M.A., Rogers, J., Sajid, M., Salzberg, S.L., Stanke, M., Tivey, A.R., White, O., Williams, D.L., Wortman, J., Wu, W., Zamanian, M., Zerlotini, A., Fraser-Liggett, C.M., Barrell, B.G., & El-Sayed, N.M. (2009). The genome of the blood fluke Schistosoma mansoni. Nature, 460(7253), 352-8. DOI: 10.1038/nature08160 PubMed Nature Faculty 1000 Must Read News

  • Marbach-Ad, G., Briken, V., El-Sayed, N.M., Frauwirth, K., Fredericksen, B., Hutcheson, S., Gao, L.Y., Joseph, S., Lee, V.T., McIver, K.S., Mosser, D., Quimby, B.B., Shields, P., Song, W., Stein, D.C., Yuan, R.T., & Smith, A.C. (2009). Assessing student understanding of host pathogen interactions using a concept inventory. Journal of Microbiology & Biology Education, 10(1), 43-50. PubMed PMC

  • Bartholomeu, D.C., Cerqueira, G.C., Leao, A.C.A., daRocha, W.D., Pais, F.S., Macedo, C., Djikeng, A., Teixeira, S.M.R., & El-Sayed, N.M. (2009). Genomic organization and expression profile of the mucin-associated surface protein (masp) family of the human pathogen Trypanosoma cruzi. Nucleic Acids Research, 120(4), 357-63. DOI: 10.1016/j.exppara.2008.09.005 PubMed NAR

  • Waisberg, M., Lobo, F.P., Cerqueira, G.C., Passos, L.K., Carvalho, O.S., El-Sayed, N.M., & Franco, G.R. (2008). Schistosoma mansoni: Microarray analysis of gene expression induced by host sex. Experimental Parasitology, 120(4), 357-63. DOI: 10.1016/j.exppara.2008.09.005 PubMed

  • Bringaud, F., Ghedin, E., El-Sayed, N.M., & Papadopoulou, B. (2008). Role of transposable elements in trypanosomatids. Microbes and Infection, 10(6), 575-81. DOI: 10.1016/j.micinf.2008.02.009 PubMed

  • Cerqueira, G.C., Bartholomeu, D.C., Darocha, W.D., Hou, L., Freitas-Silva, D.M., Machado, C.R., El-Sayed, N.M., & Teixeira, S.M. (2008). Sequence diversity and evolution of multigene families in Trypanosoma cruzi. Molecular and Biochemical Parasitology, 157(1), 65-72. DOI: 10.1016/j.molbiopara.2007.10.002 PubMed

  • Bringaud, F., Müller, M., Cerqueira, G.C., Smith, M., Rochette, A., El-Sayed, N.M., Papadopoulou, B., & Ghedin, E. (2007). Members of a large retroposon family are determinants of post-transcriptional gene expression in Leishmania. PLoS Pathogens, 3(9), 1291-307. DOI: 10.1371/journal.ppat.0030136 PubMed PMC PLoS Pathogens

  • Ghedin, E., Wang, S., Spiro, D., Caler, E., Zhao, Q., Crabtree, J., Allen, J.E., Delcher, A.L., Guiliano, D.B., Miranda-Saavedra, D., Angiuoli, S.V., Creasy, T., Amedeo, P., Haas, B., El-Sayed, N.M., Wortman, J.R., Feldblyum, T., Tallon, L., Schatz, M., Shumway, M., Koo, H., Salzberg, S.L., Schobel, S., Pertea, M. Pop, M., White, O., Barton, G.J., Carlow, C.K., Crawford, M.J., Daub, J., Dimmic, M.W., Estes, C.F., Foster, J.M., Ganatra, M., Gregory, W.F., Johnson, N.M., Jin, J., Komuniecki, R., Korf, I., Kumar, S., Laney, S., Li, B.W., Li, W., Lindlom, T.H., Lustigman, S., Ma, D., Maina, C.V., Martin, D.M., McCarter, J.P., McReynolds, L., Mitreva, M., Nutman, T.B., Parkinson, J., Peregrin-Alvarez, J.M., Poole, C., Ren, Q., Saunders, L., Sluder, A.E., Smith, K., Stanke, M., Unnasch, T.R., Ware, J., Wei, A.D., Weil, G., Williams, D.J., Williams, S.A., Fraser-Liggett, C., Slatko, B., Blaxter, M.L., & Scott, A.L. (2007). Draft genome of the filarial nematode parasite Brugia malayi. Science, 317(5845), 1756-60. DOI: 10.1126/science.1145406 PubMed PMC Science

  • Haas, B.J., Berriman, M., Hirai, H., Cerqueira, G.C, Loverde, P.T., & El-Sayed, N.M. (2007). Schistosoma mansoni genome: Closing in on a final gene set. Experimental Parasitology, 117(3), 225-8. DOI: 10.1016/j.exppara.2007.06.005 PubMed

  • Waisberg, M., Lobo, F.P., Cerqueira, G.C., Passos, L.K., Carvalho, O.S., Franco, G.R., & El-Sayed, N.M. (2007). Microarray analysis of gene expression induced by sexual contact in Schistosoma mansoni. BMC Genomics, 8, 181. DOI: 10.1186/1471-2164-8-181 PubMed PMC BMC Gen

  • Souza, R.T., Santos, M.R.M., Lima, F.M., El-Sayed, N.M., Myler, P.J., Ruiz, J.C., & da Silveira, J.F. (2007). New Trypanosoma cruzi repeated element that shows site specificity for insertion. Eukaryotic Cell, 6(7), 1228-38. DOI: 10.1128/EC.00036-07 PubMed PMC Eukaryotic Cell

  • Stelter, K., El-Sayed, N.M., & Seeber, F. (2007). The expression of a plant-type ferredoxin redox system provides molecular evidence for a plastid in the early dinoflagellate Perkinsus marinus. Protist, 158(1), 119-30. DOI: 10.1016/j.protis.2006.09.003 PubMed

  • Djikeng, A., Raverdy, S., Foster, J., Bartholomeu, D., Zhang, Y., El-Sayed, N.M., & Carlow, C. (2007). Cofactor-independent Phosphoglycerate Mutase is an essential gene in procyclic form Trypanosoma brucei. Parasitology Research, 100(4), 887-92. DOI: 10.1007/s00436-006-0332-7 PubMed Parasit Res

  • Attardo, G.M., Strickler-Dinglasan, P., Perkin, S.A., Caler, E., Bonaldo, M.F., Soares, M.B., El-Sayed, N.M., & Aksoy, S. (2006). Analysis of fat body transcriptome from the adult tsetse fly, Glossina morsitans morsitans. Insect Molecular Biology, 15(4), 411-24. DOI: 10.1111/j.1365-2583.2006.00649.x PubMed Ins Molec Bio

  • Westenberger, S.J., Cerqueira, G.C., El-Sayed, N.M., Zingales, B., Campbell, D.A., & Sturm, N.R. (2006). Trypanosoma cruzi mitochondrial maxicircles display species- and strain-specific variation and possess a conserved element in the non-coding region. BMC Genomics, 7(1), 60. DOI: 10.1186/1471-2164-7-60 PubMed PMC BMC Gen

  • Baida, R.C., Santos, M.R., Carmo, M.S., Yoshida, N., Ferreira, D., Ferreira, A.T., El-Sayed, N.M., Andersson, B., & da Silveira, J.F. (2006). Molecular characterization of serine-, alanine-, and proline-rich proteins of Trypanosoma cruzi and their possible role in host cell infection. Infection and Immunity, 74(3), 1537-46. DOI: 10.1128/IAI.74.3.1537-1546.2006 PubMed PMC Infec Immun

  • Wu, W., Niles, E.G., El-Sayed, N., Berriman, M., & LoVerde, P. (2006). Schistosoma mansoni (Platyhelminthes, Trematoda) nuclear receptors: sixteen new members and a novel subfamily. Gene, 366(2), 303-15. DOI: 10.1016/j.gene.2005.09.013 PubMed

  • Bringaud, F., Ghedin, E., Blandin, G., Bartholomeu, D., Levin, M.J., Baltz, T., & El-Sayed, N.M. (2005). Evolution of non-LTR retrotransposons in the trypanosomatid genomes:Leishmania major lost the active elements. Molecular and Biochemical Parasitology, 145(2), 158-70. DOI: 10.1016/j.molbiopara.2005.09.017 PubMed

  • Bringaud, F., Bartholomeu, D., Blandin, G., Delcher, A., Baltz, T., El-Sayed, N.M., & Ghedin, E. (2006). The Trypanosoma cruzi L1Tc and NARTc non-LTR retrotransposons show relative site specificity for insertion. Molecular Biology and Evolution, 23(2), 411-20. DOI: 10.1093/molbev/msj046 PubMed Molec Bio & Evo

  • MacLeod, A., Tweedie, A., McLellan, S., Taylor, S., Hall, N., Berriman, M., El-Sayed, N.M., Hope, M., Turner, C.M.R., & Tait, A. (2005). The genetic map and comparative analysis with physical map of Trypanosoma brucei. Nucleic Acids Research, 33(21), 6688-93. DOI: 10.1093/nar/gki980 PubMed NAR

  • Barry, J.D., Marcello, L., Morrison, L.J., Read, A.F., Lythgoe, K., Jones, N., Carrington, M., Blandin, G., Bohme, U., Caler, E., Hertz-Fowler, C., Renauld, H., El-Sayed, N., & Berriman, M. (2005). What the genome sequence is revealing about trypanosome antigenic variation. Biochemical Society Transactions, 33(5), 986-9. DOI: 10.1042/BST20050986 PubMed Biochem Soc Trans

  • Science Cover

    El-Sayed, N.M., Myler, P.J., Blandin, G., Berriman, M., Crabtree, J., Aggarwal, G., Caler, E., Renauld, H., Worthey, E.A., Hertz-Fowler, C., Ghedin, E., Peacock, C., Bartholomeu, D.C., Haas, B.J., Tran, A.N., Wortman, J.R., Alsmark, U.C., Angiuoli, S., Anupama, A., Badger, J., Bringaud, F., Cadag, E., Carlton, J.M., Cerqueira, G.C., Creasy, T., Delcher, A.L., Djikeng, A., Embley, T.M., Hauser, C., Ivens, A.C., Kummerfeld, S.K., Pereira-Leal, J.B., Nilsson, D., Peterson, J., Salzberg, S.L., Shallom, J., Silva, J.C., Sundaram, J., Westenberger, S., White, O., Melville, S.E., Donelson, J.E., Andersson, B., Stuart, K.D., & Hall, N. (2005). Comparative genomics of trypanosomatid parasitic protozoa. Science, 309(5733), 404-409. DOI: 10.1126/science.1112181 PubMed Science Nature Reviews Gen Res Highlights J Clin Invest News

  • El-Sayed, N.M., Myler, P.J., Bartholomeu, D.C., Nilsson, D., Aggarwal, G., Tran, A.N., Ghedin, E., Worthey, E.A., Delcher, A.L., Blandin, G., Westenberger, S.J., Caler, E., Cerqueira, G.C., Branche, C., Haas, B., Anupama, A., Arner, E., Aslund, L., Attipoe, P., Bontempi, E., Bringaud, F., Burton, P., Cadag, E., Campbell, D.A., Carrington, M., Crabtree, J., Darban, H., da Silveira, J.F., De Jong, P., Edwards, K., Englund, P.T., Fazelina, G., Feldblyum, T., Ferella, M., Frasch, A.C., Gull, K., Horn, D., Hou, L., Huang, Y., Kindlund, E., Klingbeil, M., Kluge, S., Koo, H., Lacerda, D., Levin, M.J., Lorenzi, H., Louie, T., Machado, C.R., McCulloch, R., McKenna, A., Mizuno, Y., Mottram, J.C., Nelson, S., Ochaya, S., Osoegawa, K., Pai, G., Parsons, M., Pentony, M., Pettersson, U., Pop, M., Ramirez, J.L., Rinta, J., Robertson, L., Salzberg, S.L., Sanchez, D.O., Seyler, A., Sharma, R., Shetty, J., Simpson, A.J., Sisk, E., Tammi, M.T., Tarleton, R., Teixeira, S., Van Aken, S., Vogt, C., Ward, P.N., Wickstead, B., Wortman, J., White, O., Fraser, C.M., Stuart, K.D., & Andersson, B. (2005). The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease. Science, 309(5733), 409-415. DOI: 10.1126/science.1112631 PubMed Science Faculty 1000 Exceptional ESI Fast Moving Front

  • Berriman M., Ghedin, E., Hertz-Fowler, C., Blandin, G., Renauld, H., Bartholomeu, D.C., Lennard, N.J., Caler, E., Hamlin, N.E., Haas, B., Bohme, U., Hannick, L., Aslett, M,A., Shallom, J., Marcello, L., Hou, L., Wickstead, B., Alsmark, U.C., Arrowsmith, C., Atkin, R.J., Barron, A.J., Bringaud, F., Brooks, K., Carrington, M., Cherevach, I., Chillingworth, T.J., Churcher, C., Clark, L.N., Corton, C.H., Cronin, A., Davies, R.M., Doggett, J., Djikeng, A., Feldblyum, T., Field, M.C., Fraser, A., Goodhead, I., Hance, Z., Harper, D., Harris, B.R., Hauser, H., Hostetler, J., Ivens, A., Jagels, K., Johnson, D., Johnson, J., Jones, K., Kerhornou, A.X., Koo, H., Larke, N., Landfear, S., Larkin, C., Leech, V., Line, A., Lord, A., Macleod, A., Mooney, P.J., Moule, S., Martin, D.M., Morgan, G.W., Mungall, K., Norbertczak, H., Ormond, D., Pai, G., Peacock, C.S., Peterson, J., Quail, M.A., Rabbinowitsch, E., Rajandream, M.A., Reitter, C., Salzberg, S.L., Sanders, M., Schobel, S., Sharp, S., Simmonds, M., Simpson, A.J., Tallon, L., Turner, C.M., Tait, A., Tivey, A.R., Van Aken, S., Walker, D., Wanless, D., Wang, S., White, B., White, O., Whitehead, S., Woodward, J., Wortman. J., Adams, M.D., Embley, T.M., Gull, K., Ullu, E., Barry, J.D., Fairlamb, A.H., Opperdoes, F., Barrell, B.G., Donelson, J.E., Hall, N., Fraser, C.M., Melville, S.E., & El-Sayed, N.M. (2005). The genome of the African trypanosome Trypanosoma brucei. Science, 309(5733), 416-22. DOI: 10.1126/science.1112642 PubMed Science Faculty 1000 Exceptional

  • Boonyaratanakornkit, B.B., Simpson, A.J., Whitehead, T.A., Fraser, C.M., El-Sayed, N.M., & Clark, D.S. (2005). Transcriptional profiling of the hyperthermophilic methanarchaeon Methanococcus jannaschii in response to lethal heat and non-lethal cold shock. Environmental Microbiology, 7(6), 789-97. DOI: 10.1111/j.1462-2920.2005.00751.x PubMed Envir Micro

  • Ouhammouch, M., Langham, G.E.,Hausner, W., Simpson, A.J., El-Sayed, N.M., & Geidushek, P. (2005). Promoter architecture and response to a positive regulator of archaeal transcription. Molecular Microbiology, 56(3), 625-37. DOI: 10.1111/j.1365-2958.2005.04563.x PubMed Molec Micro

  • Loftus, B., Anderson, I., Davies, R., Alsmark, U.C., Samuelson, J., Amedeo, P., Roncaglia, P., Berriman, M., Hirt, R.P., Mann, B.J., Nozaki, T., Suh, B., Pop, M., Duchene, M., Ackers, J., Tannich, E., Leippe, M., Hofer, M., Bruchhaus, I., Willhoeft, U., Bhattacharya, A., Chillingworth, T., Churcher, C., Hance, Z., Harris, B., Harris, D., Jagels, K., Moule, S., Mungall, K., Ormond, D., Squares, R., Whitehead, S., Quail, M.A., Rabbinowitsch, E., Norbertczak, H., Price, C., Wang, Z., Guillén, N., Gilchrist, C., Stroup, S.E., Bhattacharya, S., Lohia, A., Foster, P.G., Sicheritz-Ponten, T., Weber, C., Singh, U., Mukherjee, C., El-Sayed, N.M., Petri, W.A. Jr., Clark, C.G., Embley, T.M., Barrell, B., Fraser, C.M., & Hall, N. (2005). The genome of the protist parasite Entamoeba histolytica. Nature, 433(7028), 865-8. DOI: 10.1038/nature03291 PubMed Nature

  • Kim, D., Chiurillo, M.A., El-Sayed, N.M., Jones, K., Santos, M.R.M, Cerda, P.P., Andersson, B, Myler, P., da Silveira, J.F., & Ramirez, J.L. (2005). Telomere and subtelomere of Trypanosoma cruzi chromosomes are enriched in (pseudo)genes of retrotransposon hot spot and trans-sialidase-like gene families: the origins of T. cruzi telomeres. Gene, 346, 153-61. DOI: 10.1016/j.gene.2004.10.014 PubMed

  • Bartholomeu, D., & El-Sayed, N.M.A. (2004). Sequencing strategies for parasite genomes. In Melville, S.E. (Ed.), Methods in molecular biology: Parasite genomics protocols (pp. 1-16). Totowa, NJ: Humana Press Inc. DOI: 10.1385/1-59259-793-9:001 PubMed

  • El-Sayed, N.M, Bartholomeu, D., Ivens, A., Johnston, D.A., & LoVerde, P.T. (2004). Advances in Schistosome genomics. Trends in Parasitology, 20(4), 154-7. DOI: 10.1016/j.pt.2004.02.002 PubMed

  • LoVerde, P.T., Hirai, H., Merrick, J.M., Lee, N.H., & El-Sayed, N.M.A. (2004). Schistosoma mansoni genome project: an update. Parasitology International, 53(2), 183-192. DOI: 10.1016/j.parint.2004.01.009 PubMed

  • MBP Cover

    Ghedin, E., Bringaud, F., Peterson, J., Myler, P., Berriman, M., Ivens, A., Andersson, B., Bontempi, E., Eisen, J., Angiuoli, S., Wanless, D., Von Arx, A., Murphy, L., Lennard, N., Salzberg, S., Adams, M.D., White, O., Hall, N., Stuart, K., Fraser, C.M., & El-Sayed, N.M.A. (2004). Gene synteny and evolution of genome architecture in trypanosomatids. Molecular and Biochemical Parasitology, 143(2), 183-91. DOI: 10.1016/j.molbiopara.2003.11.012 PubMed

  • Bringaud, F., Biteau, N., Zuiderwijk, Berriman, M., El-Sayed, N.M.A., Ghedin, E., Melville, S.A., Hall, N., & T. Baltz. (2004). The ingi and RIME non-LTR retrotransposons are not randomly distributed in the genome of Trypanosoma brucei. Molecular Biology and Evolution, 21(3), 520-528. DOI: 10.1093/molbev/msh045 PubMed Mol Bio Evo

  • El-Sayed, N.M.A., Ghedin, E., Song, J., MacLeod, A., Bringaud, F., Larkin, C., Wanless, D., Peterson, J., Hou, L., Taylor, S., Tweedie, A., Biteau, N., Khalak, H.G., Lin, X., Mason, T., Hannick, L., Caler, E., Blandin, G., Bartholomeu, D., Simpson, A.J., Kaul, S., Zhao, H., Pai, G., Van Aken, S., Utterback, T., Haas, B., Koo, H.L., Umayam, L., Suh, B., Gerrard, C., Leech, V., Qi, R., Zhou, S., Schwartz, D., Feldblyum, T., Salzberg, S., Tait, A., Turner, C.M., Ullu, E., White, O., Melville, S., Adams, M.D., Fraser, C.M., & Donelson, J.E. (2003). The sequence and analysis of Trypanosoma brucei chromosome II. Nucleic Acids Research, 31(16), 4856-63. DOI: 10.1093/nar/gkg673 PubMed PMC NAR

  • Bartholomeu, D.C., Silva, R.A., Galvão, L.M.C., El-Sayed, N.M.A., Donelson, J.E. & Teixeira, S.M. (2002). Trypanosoma cruzi: RNA structure and post-transcriptional control of tubulin gene expression. Experimental Parasitology, 102(3-4), 123-133. DOI: 10.1016/S0014-4894(03)00034-1 PubMed

  • Bringaud, F. Garcia-Pérez, J.L., Heras, S.R., Ghedin, E., El-Sayed, N.M., Andersson, B., Baltz, T., & Lopez, M.C. (2002). Indentification of non-autonomous non-LTR retroposons in the genome of Trypanosoma cruzi. Molecular and Biochemical Parasitology, 124(1-2), 73-8. DOI: 10.1016/S0166-6851(02)00167-6 PubMed

  • Bringaud, F., Biteau, N., Melville, S.E., Hez, S., El-Sayed, N.M., Leech, V., Berriman, M., Hall, N., Donelson, J.E., & Baltz, T. (2002). A new expressed multigene family containing a hot spot of insertion for retroelements is associated with polymorphic subtelomeric regions of Trypanosoma brucei. Eukaryotic Cell, 1(1), 137-51. DOI: 10.1128/EC.1.1.137-151.2002 PubMed PMC Euk Cell

  • Diehl, S., Diehl, F., El-Sayed, N.M., Clayton, C., & Hoheisel, J.D. (2002). Analysis of sbadgee-specific gene expression in the bloodstream and the procyclic form of Trypanosoma brucei using a genomic DNA-microarray. Molecular and Biochemical Parasitology, 123(2), 115-23. DOI: 10.1016/S0166-6851(02)00138-X PubMed

  • LaCount, D.J., El-Sayed, N.M., Kaul, S., Wanless, D., Turner, C.M.R., & Donelson, J.E. (2001). Analysis of a donor gene region for a variant surface glycoprotein and its expression site in African trypanosomes. Nucleic Acids Research, 29(10), 2012-9. DOI: 10.1093/nar/29.10.2012 PubMed PMC NAR

  • El-Sayed, N.M.A., Hegde, P., Quackenbush, J., Melville, S.E., & Donelson, J.E. (2000). The African trypanosome genome. International Journal for Parasitology, 30(4), 329-45. DOI: 10.1016/S0020-7519(00)00015-1 PubMed

  • Donelson, J.E., Hill, K.L., & El-Sayed, N.M.A. (1999). Multiple mechanisms of immune evasion by African trypanosomes. In Pays, E. (Ed.), In the trypanosome surface (pp. 71-91). Brussels, Belgium: De Boeck & Larcier S.A..

  • Donelson, J.E., Gardner, M.J., & El-Sayed, N.M. (1999). More surprises from Kinetoplastida. Proceedings of the National Academy of Sciences USA, 96(6), 2579-81. DOI: 10.1073/pnas.96.6.2579 PubMed PMC PNAS

  • Clayton, C., Adams, M., Almeida, R., Baltz, T., Barrett, M., Bastien, P., Belli, S., Beverley, S., Biteau, N., Blackwell, J., Blaineau, C., Boshart, M., Bringaud, F., Cross, G., Cruz, A., Degrave, W., Donelson, J., El-Sayed, N., Fu, G., Ersfeld, K., Gibson, W., Gull, K., Ivens, A., Kelly, J., Lawson, D., Lebowitz, J., Majiwa, P., Matthews, K., Melville, S., Merlin, G., Michels, P., Myler, P., Norrish, A., Opperdoes, F., Papadopoulou, B., Parsons, M., Seebeck, T., Smith, D., Stuart, K., Turner, M., Ullu, E., & Vanhamme, L. (1998). Genetic nomenclature for Trypanosoma and Leishmania. Molecular and Biochemical Parasitology, 97(1-2), 221-4. PubMed Mol Bio Parasitol

  • Donelson, J.E., Hill, K.L., & El-Sayed, N.M.A. (1998). Multiple mechanisms of immune evasion by African trypanosomes. Molecular and Biochemical Parasitology, 91(1), 51-66. DOI: 10.1016/S0166-6851(97)00209-0 PubMed

  • El-Sayed, N.M.A., & Donelson, J.E. (1997). African trypanosomes have differentially expressed genes encoding homologues of the Leishmania GP63 surface protease. Journal of Biological Chemistry, 272(42), 26742-8. DOI: 10.1074/jbc.272.42.26742 PubMed J Biol Chem

  • El-Sayed, N.M.A., & Donelson, J.E. (1997). A survey of the Trypanosoma brucei rhodesiense genome using shotgun sequencing. Molecular and Biochemical Parasitology, 84(2), 167-78. DOI: 10.1016/S0166-6851(96)02792-2 PubMed

  • El-Sayed, N.M.A., & Donelson, J.E. (1997). Sequencing and mapping the African trypanosome genome. In Hide, G., Mottram, J.C., Coombs, G.H., Holmes, P.H. (Eds.), Trypanosomiasis and leishmaniasis: Biology and control (pp. 51-63). England: CAB International and the British Society for Parasitology. DOI: 10.1385/1-59259-793-9:001 PubMed

  • Morgan, R.W., El-Sayed, N.M.A., Kepa, J.K., Pedram, M., & Donelson, J.E. (1996). Differential expression of the expression site-associated gene I family in African trypanosomes. Journal of Biological Chemistry, 271(16), 9771-7. DOI: 10.1074/jbc.271.16.9771 PubMed J Biol Chem

  • El-Sayed, N.M.A., Alarcon, C.M., Beck, J.C., Sheffield, V.C., & Donelson, J.E. (1995). cDNA expressed sequence badges of Trypanosoma brucei rhodesiense provide new insights into the biology of the parasite. Molecular and Biochemical Parasitology, 73(1-2), 75-90. PubMed

  • El-Sayed, N.M.A., Patton, C.L., Harkins, P.C., Fox, R.O., & Anderson, K. (1995). Crystallization and preliminary X-ray investigation of the recombinant Trypanosoma brucei rhodesiense calmodulin. Proteins, 21(4), 354-7. DOI: 10.1002/prot.340210409 PubMed